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Longitudinal assessment of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon responses during the first year of life in HIV-1-infected infants

Abstract:

Human immunodeficiency virus type 1 (HIV-1) infection results in different patterns of viral replication in pediatric compared to adult populations. The role of early HIV-1-specific responses in viral control has not been well defined, because most studies of HIV-1-infected infants have been retrospective or cross-sectional. We evaluated the association between HIV-1-specific gamma interferon (IFN-γ) release from the cells of infants of 1 to 3 months of age and peak viral loads and mortality ...

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Publication status:
Published

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Journal:
JOURNAL OF VIROLOGY
Volume:
79
Issue:
13
Pages:
8121-8130
Publication date:
2005-07-05
DOI:
ISSN:
0022-538X
URN:
uuid:97fb5bd2-983a-4543-a88f-9929945fb22e
Source identifiers:
95298
Local pid:
pubs:95298
Language:
English

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