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Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations.

Abstract:

Hypertension is a complex disease that affects a large proportion of adult population. Although approximately half of the inter-individual variance in blood pressure (BP) level is heritable, identification of genes responsible for its regulation has remained challenging. Genome-wide association study (GWAS) is a novel approach to search for genetic variants contributing to complex diseases. We conducted GWAS for three BP traits [systolic and diastolic blood pressure (SBP and DBP); hypertensio...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddp135

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Journal:
Human molecular genetics
Volume:
18
Issue:
12
Pages:
2288-2296
Publication date:
2009-06-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:97f5a9ee-1398-4f02-871f-5b2f3c87a095
Source identifiers:
104885
Local pid:
pubs:104885

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