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How context can impact clinical trials: a multi-country qualitative case study comparison of diagnostic biomarker test interventions

Abstract:

Background: Context matters for the successful implementation of medical interventions, but its role remains surprisingly understudied. Against the backdrop of antimicrobial resistance, a global health priority, we investigated the introduction of a rapid diagnostic biomarker test (C-reactive protein, or CRP) to guide antibiotic prescriptions in outpatient settings and asked, “Which factors account for cross-country variations in the effectiveness of CRP biomarker test i... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13063-019-3215-9

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Sub department:
Tropical Medicine
Oxford college:
Green Templeton College
Role:
Author
ORCID:
0000-0002-5849-7131
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Oxford college:
Lady Margaret Hall
Role:
Author
ORCID:
0000-0002-6997-3877
Publisher:
BioMed Central Publisher's website
Journal:
Trials Journal website
Volume:
20
Issue:
1
Article number:
111
Publication date:
2019-02-08
Acceptance date:
2019-01-19
DOI:
ISSN:
1745-6215
Pmid:
30736818
Source identifiers:
972823
Language:
English
Keywords:
Pubs id:
pubs:972823
UUID:
uuid:97d733c0-303c-4a4a-b710-6e49c7ddcedf
Local pid:
pubs:972823
Deposit date:
2019-02-27

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