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Journal article

Rgs 2 gene polymorphisms as modulators of anxiety in humans?

Abstract:

Rgs2 (regulator of G-protein signalling 2) gene recently was reported as a quantitative trait gene for anxious behaviour in mice and male Rgs2 knockout mice have been shown to be more anxious than wildtype mice. Therefore we investigated four non-coding single nucleotide polymorphisms in a sample of 173 patients with panic disorder and 173 matched controls of German descent. At the genotype level all four SNPs were associated with panic disorder (p = 0.02-0.05). At the haplotype level the str...

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Publication status:
Published

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Publisher copy:
10.1007/s00702-006-0484-8

Authors


Leygraf, A More by this author
Freitag, C More by this author
Willis-Owen, SA More by this author
Krakowitzky, P More by this author
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Journal:
Journal of neural transmission (Vienna, Austria : 1996)
Volume:
113
Issue:
12
Pages:
1921-1925
Publication date:
2006-12-05
DOI:
EISSN:
1435-1463
ISSN:
0300-9564
URN:
uuid:97d02085-e2c8-4e83-8087-124783f39654
Source identifiers:
40250
Local pid:
pubs:40250

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