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Fibrosis and carcinoid syndrome: from causation to future therapy.

Abstract:

Carcinoid tumors are part of a heterogeneous group of gastrointestinal and pancreatic endocrine tumors that are characterized by their capacity to produce and secrete hormones, 5-hydroxytryptamine, tachykinins and other mediators. These substances are thought to be responsible for the collection of symptoms, which include diarrhea, flushing and wheezing, that is known as carcinoid syndrome. Fibrosis that occurs either local to or distant from the primary tumor is one of the hallmarks of carci...

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Publication status:
Published

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Publisher copy:
10.1038/nrendo.2009.51

Authors


Rockall, A More by this author
Grossman, AB More by this author
Journal:
Nature reviews. Endocrinology
Volume:
5
Issue:
5
Pages:
276-283
Publication date:
2009-05-05
DOI:
EISSN:
1759-5037
ISSN:
1759-5029
URN:
uuid:97bcc82e-caaa-41d6-9beb-d36718fc41a5
Source identifiers:
138372
Local pid:
pubs:138372

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