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Journal article

Antitumour efficacy of lymphokine-activated killer cells loaded with ricin against experimentally induced lung metastases.

Abstract:

Adoptive transfer of tumour-specific T lymphocytes loaded with ricin into tumour-bearing mice exerts a transient therapeutic effect against locally induced tumours [Cerundolo et al. (1987) Br J Cancer 55: 413]. As transferred cells preferentially locate in the lung, we studied the therapeutic effect of ricin-loaded, lymphokine-activated killer (LAK) cells on lung metastases induced by M4 or B16-F1 (F1) tumour cell injection. In vitro studies demonstrated that ricin-treated LAK cells were abou...

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Publication status:
Published

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Publisher copy:
10.1007/bf01741051

Authors


Zanovello, P More by this author
Mandruzzato, S More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine, Biomedical Research Centre
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Journal:
Cancer immunology, immunotherapy : CII
Volume:
35
Issue:
1
Pages:
27-32
Publication date:
1992-01-05
DOI:
EISSN:
1432-0851
ISSN:
0340-7004
URN:
uuid:97b74878-b92b-44f7-a33c-ff14ff8e1c85
Source identifiers:
33207
Local pid:
pubs:33207

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