- Abstract:
-
The harm that pathogens cause to hosts during infection, termed virulence, varies across species from negligible to a high likelihood of rapid death. Classic theory for the evolution of virulence is based on a trade-off between pathogen growth, transmission and host survival, which predicts that higher within-host growth causes increased transmission and higher virulence. However, using data from 61 human pathogens, we found the opposite correlation to the expected positive correlation betwee...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 440.3KB)
-
- Publisher copy:
- 10.1098/rstb.2016.0094
-
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- Publisher:
- Royal Society Publisher's website
- Journal:
- Philosophical Transactions of the Royal Society B: Biological Sciences Journal website
- Volume:
- 372
- Issue:
- 1719
- Pages:
- 20160094
- Publication date:
- 2017-03-05
- Acceptance date:
- 2016-09-26
- DOI:
- ISSN:
-
0962-8436 and 1471-2970
- Pubs id:
-
pubs:687616
- URN:
-
uri:97ad7ea6-464e-418a-a1fb-84ae0bd37bc3
- UUID:
-
uuid:97ad7ea6-464e-418a-a1fb-84ae0bd37bc3
- Local pid:
- pubs:687616
- Keywords:
- Copyright holder:
- West et al
- Copyright date:
- 2017
- Notes:
- © 2017 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
Journal article
Growth rate, transmission mode and virulence in human pathogens
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Natural Environment Research Council
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AXA Research fund
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Biotechnology and Biological Sciences Research Council
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Royal Society
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Royal Commission for the Exhibition of 1851
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