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Mood state moderates the role of serotonin in cognitive biases.

Abstract:

Reduction of the monoamine serotonin (5-HT) via the dietary manipulation of tryptophan (acute tryptophan depletion; ATD) has been shown to induce negative cognitive biases similar to those found in depression in healthy individuals. However, evidence also indicates that there can be positive effects of ATD on both mood and reinforcement processing. Here, we present two separate studies, with remarkably similar findings, which may help explain these discrepancies. In both experiments, we asses...

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Publication status:
Published

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Publisher copy:
10.1177/0269881108100257

Authors


Robinson, OJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Sahakian, BJ More by this author
Journal:
Journal of psychopharmacology (Oxford, England)
Volume:
24
Issue:
4
Pages:
573-583
Publication date:
2010-04-05
DOI:
EISSN:
1461-7285
ISSN:
0269-8811
URN:
uuid:978cfcc3-742b-422e-adf4-8fd5df204972
Source identifiers:
420726
Local pid:
pubs:420726

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