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Journal article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Abstract:

We have genotyped 14,436 nonsynonymous SNPs (nsSNPs) and 897 major histocompatibility complex (MHC) tag SNPs from 1,000 independent cases of ankylosing spondylitis (AS), autoimmune thyroid disease (AITD), multiple sclerosis (MS) and breast cancer (BC). Comparing these data against a common control dataset derived from 1,500 randomly selected healthy British individuals, we report initial association and independent replication in a North American sample of two new loci related to ankylosing s...

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Publication status:
Published

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Publisher copy:
10.1038/ng.2007.17

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Journal:
Nature genetics
Volume:
39
Issue:
11
Pages:
1329-1337
Publication date:
2007-11-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:97801877-661f-4b34-99e6-eb1ded85847b
Source identifiers:
30393
Local pid:
pubs:30393

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