Journal article icon

Journal article

An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases.

Abstract:

Arylamine N-acetyltransferases (NATs) catalyse the acetylation of arylamine, arylhydrazine and arylhydroxylamine substrates by acetyl Coenzyme A. NAT has been discovered in a wide range of eukaryotic and prokaryotic species. Although prokaryotic NATs have been implicated in xenobiotic metabolism, to date no endogenous role has been identified for the arylamine N-acetyl transfer reaction in prokaryotes. Investigating the substrate specificity of these enzymes is one approach to determining a p...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Brooke, EW More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Mulvaney, AW More by this author
Expand authors...
Journal:
Bioorganic and medicinal chemistry
Volume:
11
Issue:
7
Pages:
1227-1234
Publication date:
2003-04-05
DOI:
EISSN:
1464-3391
ISSN:
0968-0896
URN:
uuid:97602e67-b7ad-4493-a5f5-566b64c938be
Source identifiers:
110533
Local pid:
pubs:110533

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP