- Abstract:
-
Mathematical modeling is a powerful tool for unraveling the complexities of the molecular regulatory networks underlying all aspects of cell physiology. To support this claim, we review our experiences modeling the cyclin-dependent kinase (CDK) network that controls events of the eukaryotic cell cycle. The model was derived from classic experiments on the biochemistry and molecular genetics of CDKs and their partner proteins. Because the dynamical properties of CDK activity depend in large pa...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted Manuscript
- Publisher copy:
- 10.1007/s11538-014-0009-9
-
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- Publisher:
- Springer US Publisher's website
- Journal:
- Bulletin of Mathematical Biology Journal website
- Volume:
- 77
- Issue:
- 5
- Pages:
- 796-816
- Publication date:
- 2015-05-05
- DOI:
- EISSN:
-
1522-9602
- ISSN:
-
0092-8240
- URN:
-
uuid:9752f25b-d6f0-4cdf-95b5-f7622a7b790c
- Source identifiers:
-
528043
- Local pid:
- pubs:528043
- Copyright holder:
- Society for Mathematical Biology
- Copyright date:
- 2015
- Notes:
- Copyright © 2015 Society for Mathematical Biology. The final publication is available at Springer via http://dx.doi.org/10.1007/s11538-014-0009-9
Journal article
Bistability, Oscillations, and Traveling Waves in Frog Egg Extracts
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