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Tuberculosis treatment in children: The changing landscape

Abstract:

Traditionally children have been treated for tuberculosis (TB) based on data extrapolated from adults. However, we know that children present unique challenges that deserve special focus. New data on optimal drug selection and dosing are emerging with the inclusion of children in clinical trials and ongoing research on age-related pharmacokinetics and pharmacodynamics. We discuss the changing treatment landscape for drug-susceptible and drug-resistant paediatric tuberculosis in both the most ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.prrv.2020.02.002

Authors


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Division:
MSD
Department:
NDM
Marais, BJ More by this author
Schaaf, HS More by this author
Publisher:
Elsevier Publisher's website
Journal:
Paediatric Respiratory Reviews Journal website
Publication date:
2020-02-26
Acceptance date:
2020-02-18
DOI:
EISSN:
1526-0550
ISSN:
1526-0542
Pmid:
32241748
Pubs id:
1099233
Local pid:
pubs:1099233

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