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Thesis

Outcome-dependent randomisation schemes for clinical trials with fluctuations in patient characteristics

Abstract:

A clinical trial is considered in which two treatments are to be compared. Treatment allocation schemes are usually designed to assign approximately equal numbers of patients to each treatment. The purpose of this thesis is to investigate the efficiency of estimation and the effect of instability in the response variable for allocation schemes which are aimed at reducing the number of patients who receive the inferior treatment.

The general background to outcome-dependent allocatio...

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Institution:
University of Oxford
Department:
Mathematical and Physical Sciences Division
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Publication date:
1989
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Barcode:
603851033
URN:
uuid:970a8103-24fc-496e-82c0-0645f2b4e9c4
Local pid:
td:603851033

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