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A genome-wide association meta-analysis identifies new childhood obesity loci

Abstract:

Multiple genetic variants have been associated with adult obesity and a few with severe obesity in childhood; however, less progress has been made in establishing genetic influences on common early-onset obesity. We performed a North American, Australian and European collaborative meta-analysis of 14 studies consisting of 5,530 cases (≥95th percentile of body mass index (BMI)) and 8,318 controls (<50th percentile of BMI) of European ancestry. Taking forward the eight newly discovered signa...

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Publisher copy:
10.1038/ng.2247

Authors


Bradfield, JP More by this author
Timpson, NJ More by this author
Scherag, A More by this author
Lecoeur, C More by this author
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Journal:
Nature Genetics
Volume:
44
Issue:
5
Pages:
526-531
Publication date:
2012-05-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:96f4bbd6-9965-4488-bd10-c99d0e45ba6b
Source identifiers:
329389
Local pid:
pubs:329389
Language:
English

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