Journal article
Targeting TRIM5 alpha in HIV cure strategies for the CRISPR-Cas9 era
- Abstract:
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In the past decade, studies of innate immune activity against HIV-1 and other retroviruses have revealed a powerful array of host factors that can attack the virus at various stages of its life cycle in human and primate cells, raising the prospect that these antiviral factors could be manipulated in immunotherapeutic strategies for HIV infection. This has not proved straightforward: while HIV accessory genes encode proteins that subvert or destroy many of these restriction factors, others, s...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 413.3KB)
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- Publisher copy:
- 10.3389/fimmu.2017.01616
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Authors
Funding
Commonwealth Scholarship Commission
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Research Council of Norway
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British HIV Association
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Rosetrees Foundation
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Centre for AIDS research, University of Kumamoto
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Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Immunology Journal website
- Volume:
- 8
- Pages:
- 1616
- Publication date:
- 2017-11-01
- Acceptance date:
- 2017-11-08
- DOI:
- EISSN:
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1664-3224
- Source identifiers:
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809699
Item Description
- Keywords:
- Pubs id:
-
pubs:809699
- UUID:
-
uuid:96e9b092-5cc2-4193-8abf-6bcea60407dd
- Local pid:
- pubs:809699
- Deposit date:
- 2017-12-09
Terms of use
- Copyright holder:
- Rowland-Jones et al
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 Weatherley, Boswell and Rowland-Jones. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
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