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Nilabh Shastri – Towards understanding classical and non-classical MHC-I antigen processing and presentation

Abstract:

Major histocompatibility complex (MHC-I) peptide antigen processing and presentation has experienced a revived interest in the context of immuno oncology, immune surveillance escape by pathogen mutations and technical advances that accelerate vaccine design. This sheds new light on the discoveries made by Nilabh Shastri and colleagues that includes the characterisation of cryptic MHC-I peptide antigen epitopes derived from untranslated regions and the N-terminal trimming of peptide antigen...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.cellimm.2022.104638

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Target Discovery Institute
Role:
Author
ORCID:
0000-0002-8160-2446
Publisher:
Elsevier
Journal:
Cellular Immunology More from this journal
Volume:
382
Article number:
104638
Publication date:
2022-11-08
Acceptance date:
2022-11-03
DOI:
EISSN:
1090-2163
ISSN:
0008-8749
Language:
English
Keywords:
Pubs id:
1302266
Local pid:
pubs:1302266
Deposit date:
2022-11-11

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