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Journal article

In vivo CAMPATH-1H prevents GvHD following nonmyeloablative stem-cell transplantation.

Abstract:

BACKGROUND: We have investigated a novel nonmyeloablative conditioning regimen in 44 patients with hematological malignancies. The median patient age was 41 years. Many of the patients had high-risk features, including 19 patients with a previous failed transplant. METHODS: Recipient conditioning consisted of CAMPATH-1H 20 mg/day on Days -8 to -4, fludarabine 30 mg/m(2) on Days -7 to -3 and melphalan 140 mg/m(2) on Day -2. Thirty-six recipients received unmanipulated G-CSF mobilized PBSC fro...

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Publication status:
Published

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Publisher copy:
10.1080/146532401753174025

Authors


Kottaridis, PD More by this author
Milligan, DW More by this author
Chakraverty, RK More by this author
Chakrabarti, S More by this author
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Journal:
Cytotherapy
Volume:
3
Issue:
3
Pages:
197-201
Publication date:
2001
DOI:
EISSN:
1477-2566
ISSN:
1465-3249
URN:
uuid:96d5b37c-2d66-4249-9132-70d1ef58791b
Source identifiers:
13644
Local pid:
pubs:13644

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