CPAP and measures of cardiovascular risk in males with OSAS.

Journal article

Obstructive sleep apnoea syndrome (OSAS) has been associated with hypertension, stroke and myocardial ischaemia in epidemiological and observational studies. Continuous positive airway pressure (CPAP) is the treatment of choice for OSAS, but the impact of this intervention on established risk factors for cardiovascular disease remains incompletely understood. A total of 102 males with moderate-to-severe OSAS were randomised to therapeutic (n = 51) or subtherapeutic (n = 51) CPAP treatment for...

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Authors: Kohler, M; Pepperell, J; Casadei, B; Craig, S; Crosthwaite, N

• Publication status: Published
• Journal: European respiratory journal
• Volume: 32
• Issue: 6
• Pages: 1488-1496
• Publication date: 2008-12-01
• DOI: 10.1183/09031936.00026608
• EISSN: 1399-3003
• ISSN: 0903-1936
• Language: English
• Keywords: Baroreflex; Sleep Apnea, Obstructive; Middle Aged; Catecholamines; Aged; Humans; Adult; Cardiovascular Diseases; Male; Continuous Positive Airway Pressure; Treatment Outcome; Sleep; Normetanephrine; Blood Pressure; Risk Factors