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Journal article

A novel multi-antigen virally vectored vaccine against Mycobacterium avium subspecies paratuberculosis.

Abstract:

BACKGROUND: Mycobacterium avium subspecies paratuberculosis causes systemic infection and chronic intestinal inflammation in many species including primates. Humans are exposed through milk and from sources of environmental contamination. Hitherto, the only vaccines available against Mycobacterium avium subspecies paratuberculosis have been limited to veterinary use and comprised attenuated or killed organisms. METHODS: We developed a vaccine comprising a fusion construct designated HAV, con...

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Publication status:
Published

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Publisher copy:
10.1371/journal.pone.0001229

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
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Institution:
University of Oxford
Linedale, R More by this author
Dierkes, N More by this author
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Medical Research Council More from this funder
Natural Environment Research Council More from this funder
National Association of Crohn's and Colitis More from this funder
Action Medical Research More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
2
Issue:
11
Pages:
Article: e1229
Publication date:
2007
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:96b7e6cb-4edf-4b94-9e4a-f72321424085
Source identifiers:
46230
Local pid:
pubs:46230

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