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Journal article

Corticosteroids for bacterial meningitis in adults in sub-Saharan Africa.

Abstract:

BACKGROUND: In sub-Saharan Africa, bacterial meningitis is common and is associated with a high mortality. Adjuvant therapy with corticosteroids reduces mortality among adults in the developed world, but it has not been adequately tested in developing countries or in the context of advanced human immunodeficiency virus (HIV) infection. METHODS: We conducted a randomized, double-blind, placebo-controlled trial of dexamethasone (16 mg twice daily for 4 days) and an open-label trial of intramus...

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Publication status:
Published

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Publisher copy:
10.1056/nejmoa065711

Authors


Scarborough, M More by this author
Gordon, SB More by this author
Whitty, CJ More by this author
Njalale, Y More by this author
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Journal:
The New England journal of medicine
Volume:
357
Issue:
24
Pages:
2441-2450
Publication date:
2007-12-05
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
URN:
uuid:96aa3483-371b-4ff5-90c3-83d4d271f0d2
Source identifiers:
120073
Local pid:
pubs:120073

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