Shigella flexneri Spa15 crystal structure verified in solution by double electron electron resonance
Shigella flexneri Spa15 is a chaperone of the type 3 secretion system, which binds a number of effectors to ensure their stabilization prior to secretion. One of these effectors is IpgB1, a mimic of the human Ras-like Rho guanosine triphosphatase RhoG. In this study, Spa15 alone and in complex with IpgB1 has been studied by double electron electron resonance, an experiment that gives distance information showing the spacial separation of attached spin labels. This distance is explain... Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
- Publisher's version
+ Engineering and Physical Sciences Research Council More from this funder
Funding agency for:
James E. D. Lillington
- Copyright holder:
- Elsevier Ltd.
- Copyright date:
- Copyright © 2010 Elsevier Ltd. Open access under CC BY license. Open Access funded by Wellcome Trust.
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