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Thesis

Investigating the role of the anti-malarial drug Atovaquone in anti-cancer therapy

Abstract:

Radiotherapy (XRT) is used in over half of all cancer treatment regimens and can be administered alone or in tandem with chemotherapeutics to improve clinical outcomes. Sub-physiological levels of oxygen (hypoxia) is a feature of many solid tumours and can diminish the effectiveness of anti-cancer treatments. Though its detrimental impact on treatment efficacy was first realised over half a century ago, hypoxia endures as a significant barrier to improving clinical outcomes.

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Division:
MSD
Department:
Oncology
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:96a0b3ff-980b-40b5-a254-cdea9e4080f5

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