Journal article
111In-BnDTPA-F3: An Auger electron-emitting radiotherapeutic agent that targets nucleolin
- Abstract:
-
Introduction: The F3 peptide (KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK), a fragment of the human high mobility group protein 2, binds nucleolin. Nucleolin is expressed in the nuclei of normal cells but is also expressed on the membrane of some cancer cells. The goal was to investigate the use of 111In-labeled F3 peptide for Auger electron-targeted radiotherapy. Methods: F3 was labeled with fluorescein isothiocyanate (FITC) for confocal microscopy and conjugated to p-SCNbenzyl- diethylenetriaminepentaa...
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- Publisher copy:
- 10.1186/2191-219X-2-9
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Bibliographic Details
- Journal:
- EJNMMI Research
- Volume:
- 2
- Issue:
- 1
- Pages:
- 1-11
- Publication date:
- 2012-07-23
- DOI:
- EISSN:
-
2191-219X
- Source identifiers:
-
396163
Item Description
- Pubs id:
-
pubs:396163
- UUID:
-
uuid:969c5e62-48e7-450e-b6f6-b8df44cc5477
- Local pid:
- pubs:396163
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2012
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