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Bleeding Risk with Long-Term Low-Dose Aspirin: A Systematic Review of Observational Studies.

Abstract:

Background
Low-dose aspirin has proven effectiveness in secondary and primary prevention of cardiovascular events, but is also associated with an increased risk of major bleeding events. For primary prevention, this absolute risk must be carefully weighed against the benefits of aspirin; such assessments are currently limited by a lack of data from general populations.

Methods
Systematic searches of Medline and Embase were conducted to identify observational studies pub...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0160046

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Publisher:
Public Library of Science
Journal:
PLoS One More from this journal
Volume:
11
Issue:
8
Publication date:
2016-08-04
Acceptance date:
2016-05-30
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Pmid:
27490468
Language:
English
Keywords:
Pubs id:
pubs:638621
UUID:
uuid:9697504f-2253-428c-bfa9-8f2d3b1f5214
Local pid:
pubs:638621
Source identifiers:
638621
Deposit date:
2016-11-09

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