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Mass drug administrations with dihydroartemisinin-piperaquine and single low dose primaquine to eliminate Plasmodium falciparum have only a transient impact on Plasmodium vivax: Findings from randomised controlled trials

Abstract:

Background: Mass administrations of antimalarial drugs (MDA) have reduced the incidence and prevalence of Pfalciparum infections in a trial in the Greater Mekong Subregion. Here we assess the impact of the MDA on Pvivax infections.

Methods: Between May 2013 and July 2017, four villages in each Myanmar, Vietnam, Cambodia and Lao PDR were selected based on high prevalence ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0228190

Authors


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Role:
Author
ORCID:
0000-0002-5490-8968
More by this author
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0003-3197-9891
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Role:
Author
ORCID:
0000-0002-4101-5706
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Grant:
106698/B/14/Z milestone
106698/Z/14/A milestone
101148/Z/13/Z
Publisher:
Public Library of Science
Journal:
PLoS ONE More from this journal
Volume:
15
Issue:
2
Article number:
e0228190
Place of publication:
United States
Publication date:
2020-02-05
Acceptance date:
2020-01-08
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Pmid:
32023293
Language:
English
Keywords:
Pubs id:
1085384
Local pid:
pubs:1085384
Deposit date:
2020-03-08

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