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Ancestral inference on gene trees under selection.

Abstract:

The extent to which natural selection shapes diversity within populations is a key question for population genetics. Thus, there is considerable interest in quantifying the strength of selection. A full likelihood approach for inference about selection at a single site within an otherwise neutral fully linked sequence of sites is described here. A coalescent model of evolution is used to model the ancestry of a sample of DNA sequences which have the selected site segregating. The mutation mod...

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Publication status:
Published

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Publisher copy:
10.1016/j.tpb.2004.06.006

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Institution:
University of Oxford
Department:
Oxford, MPLS, Statistics
Journal:
Theoretical population biology
Volume:
66
Issue:
3
Pages:
219-232
Publication date:
2004-11-05
DOI:
EISSN:
1096-0325
ISSN:
0040-5809
URN:
uuid:967d6ad3-0dbd-4c68-96cd-cec3eafb4acf
Source identifiers:
97706
Local pid:
pubs:97706

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