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Journal article

Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: a multicentre randomised trial.

Abstract:

BACKGROUND: Policies of UK clinicians regarding the duration of chemotherapy for patients with advanced colorectal cancer are not consistent. We aimed to compare effectiveness of continuous and intermittent chemotherapy in such patients. METHODS: Patients who responded or had stable disease after receiving 12 weeks of the regimens described by de Gramont and Lokich, or raltitrexed chemotherapy, were randomised to either intermittent (a break in chemotherapy, re-starting on the same drug on p...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Role:
Author
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Journal:
Lancet
Volume:
361
Issue:
9356
Pages:
457-464
Publication date:
2003-02-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:966484a6-5204-40b6-afce-17949d9ed5ab
Source identifiers:
164159
Local pid:
pubs:164159

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