Journal article

Mechanisms in endocrinology: diabetic cardiomyopathy: pathophysiology and potential metabolic interventions state of the art review

Abstract:: Heart failure is a major cause of morbidity and mortality in type 2 diabetes. Type 2 diabetes contributes to the development of heart failure through a variety of mechanisms, including disease-specific myocardial structural, functional and metabolic changes. This review will focus on the contemporary contributions of state of the art non-invasive technologies to our understanding of diabetic cardiomyopathy, including data on cardiac disease phenotype, cardiac energy metabolism and energetic deficiency, ectopic and visceral adiposity, diabetic liver disease, metabolic modulation strategies and cardiovascular outcomes with new classes of glucose-lowering therapies.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Levelt, E., Gulsin, G., Neubauer, S., & McCann, G. (2018). Mechanisms in endocrinology: diabetic cardiomyopathy: pathophysiology and potential metabolic interventions state of the art review. European Journal of Endocrinology, 178(4), R127–R139.

MLA Style

Levelt, E., et al. “Mechanisms in Endocrinology: Diabetic Cardiomyopathy: Pathophysiology and Potential Metabolic Interventions State of the Art Review.” European Journal of Endocrinology, vol. 178, no. 4, BioScientifica, 2018, pp. R127–R139.

Chicago Style

Levelt, E, G Gulsin, S Neubauer, and G McCann. 2018. “Mechanisms in Endocrinology: Diabetic Cardiomyopathy: Pathophysiology and Potential Metabolic Interventions State of the Art Review.” European Journal of Endocrinology 178 (4): R127–R139.
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Files:: MECHANISMS IN ENDOCRINOLOGY: Diabetic cardiomyopathy: pathophy...

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Publisher copy:: 10.1530/EJE-17-0724

Authors

+ Levelt, E More by this author

Role:: Author

+ Gulsin, G More by this author

Role:: Author

+ Neubauer, S More by this author

Institution:: University of Oxford
Division:: MSD
Department:: RDM
Sub department:: RDM Strategic
Oxford college:: Christ Church
Role:: Author

+ McCann, G More by this author

Role:: Author

Publisher:: BioScientifica
Journal:: European Journal of Endocrinology More from this journal
Volume:: 178
Issue:: 4
Pages:: R127–R139
Publication date:: 2018-04-01
Acceptance date:: 2018-02-12
DOI:: 10.1530/EJE-17-0724
EISSN:: 1479-683X
ISSN:: 0804-4643
Pmid:: 29440374

Language:: English
Keywords:: animals

energy metabolism

humans

diabetes mellitus; type 2

diabetic cardiomyopathies

hypoglycemic agents
Pubs id:: pubs:825469
UUID:: uuid:9664367d-a0b8-4504-a2b9-6bf402f85904
Local pid:: pubs:825469
Source identifiers:: 825469
Deposit date:: 2019-02-04

Terms of use

Copyright holder:: Levelt et al
Copyright date:: 2018
Notes:: © 2018 The authors 2018. This work is licensed under a Creative Commons
Attribution 4.0 International License.

Licence:: CC Attribution (CC BY)

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