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Acoustic Cavitation Enhances Focused Ultrasound Ablation with Phase-Shift Inorganic Perfluorohexane Nanoemulsions: An In Vitro Study Using a Clinical Device

Abstract:

Purpose. To investigate whether acoustic cavitation could increase the evaporation of a phase-shift inorganic perfluorohexane (PFH) nanoemulsion and enhance high intensity focused ultrasound (HIFU) ablation. Materials and Methods. PFH was encapsulated by mesoporous silica nanocapsule (MSNC) to form a nanometer-sized droplet (MSNC-PFH). It was added to a tissue-mimicking phantom, whereas phosphate buffered saline (PBS) was added as a control (PBS-control). HIFU (P ac = 150 W, t = 5/10 s) expos...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1155/2016/7936902

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Grant:
National Key Basic Research Program, Grant 2011 CB707900
Publisher:
Hindawi Publishing Corporation Publisher's website
Journal:
BioMed Research International Journal website
Volume:
2016
Pages:
Article ID 7936902
Acceptance date:
2016-05-15
DOI:
EISSN:
2314-6141
ISSN:
2314-6133
Pubs id:
pubs:636535
URN:
uri:96506668-af99-4095-9bdc-e27dcd646031
UUID:
uuid:96506668-af99-4095-9bdc-e27dcd646031
Local pid:
pubs:636535

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