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Journal article

DNA-immunisation with dengue virus E protein domains I/II, but not domain III, enhances Zika, West Nile and Yellow Fever virus infection

Abstract:

Dengue virus (DENV), the causative agent of dengue disease, is among the most important mosquito-borne pathogens worldwide. DENV is composed of four closely related serotypes and belongs to the Flaviviridae family alongside other important arthropod-borne viral pathogens such as Zika virus (ZIKV), West Nile virus (WNV) and Yellow Fever virus (YFV). After infection, the antibody response is mostly directed to the viral E glycoprotein which is composed of three structural domains named DI, DII ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0181734

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
ORCID:
0000-0002-0012-5247
Publisher:
Public Library of Science
Journal:
PloS one More from this journal
Volume:
12
Issue:
7
Pages:
19
Publication date:
2017-07-25
Acceptance date:
2017-07-06
DOI:
EISSN:
1932-6203
Pmid:
28742857
Language:
English
Keywords:
Pubs id:
pubs:863433
UUID:
uuid:96469cea-846d-4c54-a757-ff7429eb952b
Local pid:
pubs:863433
Source identifiers:
863433
Deposit date:
2018-07-05

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