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Improved detection of aneuploid blastocysts using a new 12-chromosome FISH test.

Abstract:

Fluorescence in-situ hybridization (FISH) has been the principal method used for the identification and preferential transfer of chromosomally normal embryos, in the context of both preimplantation genetic diagnosis (PGD) and screening (PGS). Generally, the probe combinations used during PGS have focused on chromosomes frequently identified as abnormal in prenatal samples or material derived from first-trimester spontaneous abortions. Recent data, however, obtained with the use of comparative...

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Publication status:
Published

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Publisher copy:
10.1016/j.rbmo.2009.10.015

Authors


Fragouli, E More by this author
Katz-Jaffe, M More by this author
Schoolcraft, W More by this author
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Journal:
Reproductive biomedicine online
Volume:
20
Issue:
1
Pages:
92-97
Publication date:
2010-01-05
DOI:
EISSN:
1472-6491
ISSN:
1472-6483
URN:
uuid:964642ca-31ed-4042-9087-c511148910cd
Source identifiers:
248387
Local pid:
pubs:248387

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