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A comparison of two short-course primaquine regimens for the treatment and radical cure of Plasmodium vivax malaria in Thailand.

Abstract:

Thai adult males (N = 85) with acute Plasmodium vivax malaria and normal glucose-6-phosphate dehydrogenase screening were randomized to receive 30 mg or 60 mg primaquine daily for 7 days (N = 43 and 42, respectively). The regimens were well tolerated and all patients recovered fully. Median fever clearance (47 hours; range 4 to 130 hours), mean + or - SD parasite clearance times (87.7 + or - 25.3 hours), gametocyte clearance, and adverse effects were similar in the 2 groups. Two patients, 1 f...

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Publication status:
Published

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Publisher copy:
10.4269/ajtmh.2010.09-0428

Authors


Pukrittayakamee, S More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Chotivanich, K More by this author
Singhasivanon, P More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
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Journal:
The American journal of tropical medicine and hygiene
Volume:
82
Issue:
4
Pages:
542-547
Publication date:
2010-04-05
DOI:
EISSN:
1476-1645
ISSN:
0002-9637
URN:
uuid:963162e7-f947-435b-8c08-656feba27db9
Source identifiers:
53369
Local pid:
pubs:53369

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