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Decellularized scaffold of cryopreserved rat kidney retains its recellularization potential.

Abstract:

The multi-cellular nature of renal tissue makes it the most challenging organ for regeneration. Therefore, till date whole organ transplantations remain the definitive treatment for the end stage renal disease (ESRD). The shortage of available organs for the transplantation has, thus, remained a major concern as well as an unsolved problem. In this regard generation of whole organ scaffold through decellularization followed by regeneration of the whole organ by recellularization is being view...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0173040

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Obstetrics & Gynaecology
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Grant:
PURSE Grant to Center for Stem Cell and Tissue Engineering, Panjab University Chandigarh, India (vide letters no. 136-137/RPC/ 3/6/2016- 38/RPC/29/4/2016)
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS One Journal website
Volume:
12
Issue:
3
Publication date:
2017-03-07
Acceptance date:
2017-02-14
DOI:
EISSN:
1932-6203
Pubs id:
pubs:685446
URN:
uri:961430ef-09e4-49e8-9654-77a6d3f008f7
UUID:
uuid:961430ef-09e4-49e8-9654-77a6d3f008f7
Local pid:
pubs:685446

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