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Pedunculopontine stimulation from primate to patient

Abstract:
Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) is a novel neurosurgical therapy developed to address symptoms of gait freezing and postural instability in Parkinson's disease and related disorders. Here we summarise our non-human primate investigations of relevance to our surgical targeting of the PPN and relate the primate research to initial clinical experience of PPN DBS. © Springer-Verlag 2010.

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Publisher copy:
10.1007/s00702-011-0631-8

Authors


Pereira, EAC More by this author
Jenkinson, N More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
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Journal:
Journal of Neural Transmission
Volume:
118
Issue:
10
Pages:
1453-1460
Publication date:
2011-10-05
DOI:
EISSN:
1435-1463
ISSN:
0300-9564
URN:
uuid:95d45b01-d137-41d0-ac20-5f52cc2776da
Source identifiers:
206366
Local pid:
pubs:206366

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