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Tangential Networks of Precocious Neurons and Early Axonal Outgrowth in the Embryonic Human Forebrain

Abstract:

We used a combination of immunohistochemistry and carbocyanine dye tracing to study neurons and their processes in the human embryonic forebrain, 4–7 weeks after conception, before the onset of synaptogenesis.Wediscovered a widespread network of precocious MAP2 (microtubule-associated protein 2)-immunoreactive cells, with long, nonaxonal processes, before the appearance of the cortical plate and the establishment of thalamocortical connectivity. Dye tracing revealed that the processes of thes...

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Journal:
Journal of Neuroscience
Publication date:
2004
Local pid:
ora:834
Subjects:

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