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Tangential Networks of Precocious Neurons and Early Axonal Outgrowth in the Embryonic Human Forebrain

Abstract:

We used a combination of immunohistochemistry and carbocyanine dye tracing to study neurons and their processes in the human embryonic forebrain, 4–7 weeks after conception, before the onset of synaptogenesis.Wediscovered a widespread network of precocious MAP2 (microtubule-associated protein 2)-immunoreactive cells, with long, nonaxonal processes, before the appearance of the cortical plate and the establishment of thalamocortical connectivity. Dye tracing revealed that the processes of thes...

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Authors


Contributors

Otellin, Vladimir
Molnar, Zoltan
Bystron, Irina
Blakemore, Colin
Publisher:
Society of Neuroscience
Journal:
Journal of Neuroscience
Issue:
25
Publication date:
2004-01-01
Source identifiers:
http://sers009b.sers.ox.ac.uk/archive/00000971/
Subjects:
UUID:
uuid:95b1b015-1e6e-491c-ab36-8d71bc3b2367
Local pid:
ora:834
Deposit date:
2012-11-15

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