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Disease evolution in multiple sclerosis

Abstract:

Multiple sclerosis is a long-term disease that evolves over a period of 30 to 40 years with progressive accumulation of unremitting disability. When developing treatments for multiple sclerosis, it is important to be able to measure accurately the impact of treatments on disability progression. An analysis of 31 previous clinical trials revealed that small changes in EDSS scores measured across two or three years may be insufficiently sensitive to detect sustained changes in disability reliab...

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Publication status:
Published

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Publisher copy:
10.1007/s00415-006-6002-y

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Volume:
253
Issue:
SUPPL. 6
Pages:
3-8
Host title:
JOURNAL OF NEUROLOGY
Publication date:
2006-11-01
DOI:
EISSN:
1432-1459
ISSN:
0340-5354
Source identifiers:
40167
Keywords:
Pubs id:
pubs:40167
UUID:
uuid:95aaab8b-5e98-4c01-b5fd-f71ec4aaeb11
Local pid:
pubs:40167
Deposit date:
2013-11-16

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