Journal article
Phase-transfer-catalysed synthesis of pyrroloindolines and pyridoindolines by a hydrogen-bond-assisted isocyanide cyclization cascade.
- Abstract:
-
A cascade reaction that generates pyrrolo- and pyridoindoline motifs from isocyanide precursors under phase-transfer conditions is described. This transformation proceeds at room temperature in the presence of a quaternary ammonium catalyst and base to generate functionalized products containing an all-carbon quaternary stereocentre. Quantum chemical calculations demonstrated that intramolecular general acid catalysis plays a key accelerating role through stabilization of developing charge in...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
+ Croatian Science Foundation
More from this funder
Funding agency for:
Gredičak, M
Grant:
02.03./158
Bibliographic Details
- Publisher:
- Wiley
- Journal:
- Chemistry - A European Journal More from this journal
- Volume:
- 20
- Issue:
- 11
- Pages:
- 3005-3009
- Publication date:
- 2014-02-12
- DOI:
- EISSN:
-
1521-3765
- ISSN:
-
0947-6539
Item Description
- Language:
-
English
- Keywords:
- UUID:
-
uuid:95363230-7163-431d-b81b-a59a0c90bb7b
- Local pid:
-
pubs:449258
- Source identifiers:
-
449258
- Deposit date:
-
2014-02-23
Terms of use
- Copyright holder:
- Wiley-VCH Verlag
- Copyright date:
- 2014
- Notes:
- © 2014 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim. Published by Wiley-VCH Verlag on behalf of ChemPubSoc Europe, in assocation with the Asian Chemical Editorial Society (ACES). The final version is available online from Wiley-VCH Verlag at: [10.1002/chem.201400192].
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record