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Sex-specific differences in hepatic fat oxidation and synthesis may explain the higher propensity for NAFLD in men

Abstract:

Context and Objective: In most populations a greater proportion of men have hepatic steatosis than women. Sex-specific differences in hepatic dietary fatty acid (FA) metabolism have not been well characterized. We compared fasting and postprandial hepatic FA synthesis (de novo lipogenesis [DNL]) and oxidation in men and women.
Participants and Methods: Fasting and postprandial hepatic FA metabolism was studied in 22 healthy men (n = 11) and ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1210/jc.2015-2649

Authors


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Role:
Author
ORCID:
0000-0003-4928-1256
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
ORCID:
0000-0001-9882-8874
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM Strategic
Oxford college:
Christ Church
Role:
Author
Publisher:
Endocrine Society
Journal:
Journal of Clinical Endocrinology and Metabolism More from this journal
Volume:
100
Issue:
12
Pages:
4425–4433
Publication date:
2015-12-01
Acceptance date:
2015-09-22
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
Pmid:
26414963
Language:
English
Keywords:
Pubs id:
pubs:581158
UUID:
uuid:95266c0c-557f-4352-b181-010342c995ce
Local pid:
pubs:581158
Source identifiers:
581158
Deposit date:
2019-06-16

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