Hemochromatosis gene (HFE) mutations in South East Asia: a potential for iron overload.

Pointon, JJ; Viprakasit, V; Miles, KL; Livesey, KJ; Steiner, M; O'Riordan, S; Hien, TT; Merryweather-Clarke, AT; Robson, KJ

Abstract:

Hereditary hemochromatosis (HH) is an autosomal recessive disease caused by mutations in the HFE gene that mainly affects populations of European descent. Recently a novel mutation (IVS5+1 G-->A) has been described in a Vietnamese patient with HH that was not detected in a European control population. We have developed a novel method to screen for this mutation based on restriction enzyme digestion of a PCR product using a modified forward primer. We have screened 314 Vietnamese people fro...

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APA Style

Pointon, J. J., Viprakasit, V., Miles, K. L., Livesey, K. J., Steiner, M., O'Riordan, S., Hien, T. T., Merryweather-Clarke, A. T., & Robson, K. J. (2003). Hemochromatosis gene (HFE) mutations in South East Asia: a potential for iron overload. Blood Cells, Molecules and Diseases, 30(3), 302–306.

MLA Style

Pointon, J. J., et al. “Hemochromatosis Gene (HFE) Mutations in South East Asia: a Potential for Iron Overload.” Blood Cells, Molecules and Diseases, vol. 30, no. 3, Blood cells, molecules and diseases, 2003, pp. 302–06.

Chicago Style

Pointon, JJ, V Viprakasit, KL Miles, KJ Livesey, M Steiner, S O'Riordan, TT Hien, AT Merryweather-Clarke, and KJ Robson. 2003. “Hemochromatosis Gene (HFE) Mutations in South East Asia: a Potential for Iron Overload.” Blood Cells, Molecules and Diseases 30 (3): 302–6.
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