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Journal article

Thymus-independent IgM and IgG responses in mice to flagellar antigens.

Abstract:

The antibody response to the dinitrophenyl (DNP) hapten was studied in mice depleted of T cells. It was found that 'nude' mise or neonatally thymectomized mice which had also been injected with antilymphocyte serum responded after the injection of DNP conjugated to the thymus independent carrier, Salmonella flagella (DNP Fla), but not the thymus dependent carrier, fowl γ globulin. The IM primary response was completely normal, but the IgG response was about 1/5-1/3 of normal. The IgM secondar...

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
International archives of allergy and applied immunology
Volume:
46
Issue:
4
Pages:
600-611
Publication date:
1974-01-01
ISSN:
0020-5915
URN:
uuid:95160d09-ae85-4462-a215-15abcda5561d
Source identifiers:
481924
Local pid:
pubs:481924

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