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Journal article

Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.

Abstract:

Invasion of host erythrocytes is essential to the life cycle of Plasmodium parasites and development of the pathology of malaria. The stages of erythrocyte invasion, including initial contact, apical reorientation, junction formation, and active invagination, are directed by coordinated release of specialized apical organelles and their parasite protein contents. Among these proteins, and central to invasion by all species, are two parasite protein families, the reticulocyte-binding protein h...

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Publication status:
Published

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Publisher copy:
10.1038/nature13715

Authors


Wright, KE More by this author
Hjerrild, KA More by this author
Bartlett, J More by this author
Douglas, AD More by this author
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Publisher:
Nature Publishing Group
Journal:
Nature
Volume:
515
Issue:
7527
Pages:
427-430
Publication date:
2014-11-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:95052b93-19c0-446a-bb5c-6a51770aa417
Source identifiers:
481514
Local pid:
pubs:481514

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