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Comparing model-based and model-free analysis methods for QUASAR arterial spin labeling perfusion quantification

Abstract:

Amongst the various implementations of arterial spin labeling MRI methods for quantifying cerebral perfusion, the QUASAR method is unique. By using a combination of labeling with and without flow suppression gradients, the QUASAR method offers the separation of macrovascular and tissue signals. This permits local arterial input functions to be defined and "model-free" analysis, using numerical deconvolution, to be used. However, it remains unclear whether arterial spin labeling data are best ...

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Publisher copy:
10.1002/mrm.24372

Authors


Chappell, MA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Petersen, ET More by this author
Journal:
Magnetic Resonance in Medicine
Volume:
69
Issue:
5
Pages:
1466-1475
Publication date:
2013-05-05
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
URN:
uuid:94f1e07e-4fbf-489b-ad65-c2eb844bc2bd
Source identifiers:
403294
Local pid:
pubs:403294

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