Journal article icon

Journal article

Thiyl radicals react with nitric oxide to form S-nitrosothiols with rate constants near the diffusion-controlled limit.

Abstract:

A possible route to S-nitrosothiols in biology is the reaction between thiyl radicals and nitric oxide. D. Hofstetter et al. (Biochem. Biophys. Res. Commun.360:146-148; 2007) claimed an upper limit of (2.8+/-0.6)x10(7) M(-1)s(-1) for the rate constant between thiyl radicals derived from glutathione and nitric oxide, and it was suggested that under physiological conditions S-nitrosation via this route is negligible. In the present study, thiyl radicals were generated by pulse radiolysis, and t...

Expand abstract

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Wardman, P More by this author
Czapski, G More by this author
Goldstein, S More by this author
Journal:
Free radical biology and medicine
Volume:
44
Issue:
12
Pages:
2013-2018
Publication date:
2008-06-05
DOI:
EISSN:
1873-4596
ISSN:
0891-5849
URN:
uuid:94dcadf8-06b7-4b2b-a985-951cc083d86e
Source identifiers:
254929
Local pid:
pubs:254929

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP