In connection with prospective 18F-PET imaging studies, the potential for enzymatic synthesis of fluorine-labelled glycosides of small molecules was investigated. Approaches to the enzymatic synthesis of anomeric phosphates of d-gluco-configured fluorosugars proved ineffective. In contrast, starting in the d-galacto series and relying on the consecutive action of Escherichia coli galactokinase (GalK), galactose-1-phosphate uridylyltransferase (GalPUT), uridine-5′-diphosphogalactose 4-epimeras...Expand abstract
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- Caputi et al.
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articletitle: A one-pot enzymatic approach to the O-fluoroglucoside of N-methylanthranilate
journaltitle: Bioorganic and Medicinal Chemistry
copyright: Copyright © 2013 The Authors. Published by Elsevier Ltd.
© 2013 The Authors. Published by Elsevier Ltd. Open Access under a CC BY License.