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Effect of temperature in focal ischemia of rat brain studied by 31P and 1H spectroscopic imaging.

Abstract:

31P, 1H and lactate spectroscopic imaging was used to evaluate' the effects of hypothermia on focal cerebral ischemia produced by middle cerebral artery occlusion. The effects on high energy phosphate metabolism, pH, lactate and NAA were investigated in 24 spontaneously hypertensive rats subjected to either permanent or transient ischemia. Under either normothermic (37.5 degrees C) or hypothermic (32 degrees C) conditions, with permanent 6-h occlusion, there was little difference between grou...

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Publication status:
Published

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Publisher copy:
10.1002/mrm.1910370307

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Stroke and Geratology
Role:
Author
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Journal:
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine More from this journal
Volume:
37
Issue:
3
Pages:
346-354
Publication date:
1997-03-01
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
Language:
English
Keywords:
Pubs id:
pubs:80193
UUID:
uuid:94a7bd65-df53-4d59-b651-58252f531db3
Local pid:
pubs:80193
Source identifiers:
80193
Deposit date:
2012-12-19

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