- Abstract:
-
PURPOSE: Gap junctional coupling between rod and cone photoreceptor cells is regulated by light and the circadian clock, and contributes to retinal light adaptation. Phosphorylation of connexin 36 (Cx36) has been proposed as the mechanism involved. We investigated whether retinal Cx36 is also regulated at the level of transcript and protein expression. METHODS: At specific time points in a diurnal or circadian cycle, Cx36 protein was assessed by Western blotting and immunohistochemistry, and...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1167/iovs.12-10375
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- Journal:
- Investigative ophthalmology and visual science
- Volume:
- 54
- Issue:
- 1
- Pages:
- 821-829
- Publication date:
- 2013-01-05
- DOI:
- EISSN:
-
1552-5783
- ISSN:
-
0146-0404
- URN:
-
uuid:94877fd3-4de7-4d4b-90d6-bd31dfb36765
- Source identifiers:
-
374247
- Local pid:
- pubs:374247
- Copyright date:
- 2013
Journal article
Diurnal and circadian regulation of connexin 36 transcript and protein in the mammalian retina.
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