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The p53 codon 72 polymorphism (rs1042522) is associated with proliferative vitreoretinopathy: the Retina 4 Project.

Abstract:

PURPOSE: To compare the distribution of a p53 gene polymorphism among European subjects undergoing primary retinal detachment (RD) surgery in relation to the development of proliferative vitreoretinopathy (PVR). DESIGN: Case-controlled gene association study conducted as a component of the Retina 4 Project (a European multicenter study). PARTICIPANTS AND CONTROLS: Five hundred fifty DNA samples, 134 with PVR secondary to primary RD and 416 with RD without PVR. METHODS: The p53 codon 72 polym...

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Authors


Pastor-Idoate, S More by this author
Rodriguez-Hernández, I More by this author
Fernández, I More by this author
García-Gutierrez, MT More by this author
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Journal:
Ophthalmology
Volume:
120
Issue:
3
Pages:
623-628
Publication date:
2013-03-05
DOI:
EISSN:
1549-4713
ISSN:
0161-6420
URN:
uuid:947e8278-653e-4bbd-993d-4a0abd22a84b
Source identifiers:
365528
Local pid:
pubs:365528

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