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One PRDM is not enough for germ cell development.

Abstract:
Developmentally regulated expression of the transcriptional repressor Prdm1 (Blimp1) in the early mammalian embryo controls global epigenetic changes required for specification of primordial germ cells. A new study demonstrates that a close family member, Prdm14, similarly activated in response to Bmp and Smad signals, also has an essential role during establishment of the germ cell lineage. © 2008 Nature Publishing Group.
Publication status:
Published

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Publisher copy:
10.1038/ng0808-934

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Nature genetics
Volume:
40
Issue:
8
Pages:
934-935
Publication date:
2008-08-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:94649925-88ce-4e49-99f9-18fe10babea3
Source identifiers:
15367
Local pid:
pubs:15367

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