Journal article
One PRDM is not enough for germ cell development.
- Abstract:
- Developmentally regulated expression of the transcriptional repressor Prdm1 (Blimp1) in the early mammalian embryo controls global epigenetic changes required for specification of primordial germ cells. A new study demonstrates that a close family member, Prdm14, similarly activated in response to Bmp and Smad signals, also has an essential role during establishment of the germ cell lineage. © 2008 Nature Publishing Group.
- Publication status:
- Published
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- Publisher copy:
- 10.1038/ng0808-934
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Authors
Bibliographic Details
- Journal:
- Nature genetics
- Volume:
- 40
- Issue:
- 8
- Pages:
- 934-935
- Publication date:
- 2008-08-01
- DOI:
- EISSN:
-
1546-1718
- ISSN:
-
1061-4036
- Source identifiers:
-
15367
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:15367
- UUID:
-
uuid:94649925-88ce-4e49-99f9-18fe10babea3
- Local pid:
- pubs:15367
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2008
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