- Abstract:
-
A tetrodotoxin-sensitive persistent sodium current, I(pNa), was found in guinea pig ventricular myocytes by whole-cell patch clamping. This current was characterized in cells derived from the basal left ventricular subendocardium, midmyocardium, and subepicardium. Midmyocardial cells show a statistically significant (P<0.05) smaller I(pNa) than subendocardial and subepicardial myocytes. There was no significant difference in I(pNa) current density between subepicardial and subendocardial c...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1161/01.res.87.10.910
-
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- Journal:
- Circulation research
- Volume:
- 87
- Issue:
- 10
- Pages:
- 910-914
- Publication date:
- 2000-11-05
- DOI:
- EISSN:
-
1524-4571
- ISSN:
-
0009-7330
- URN:
-
uuid:943eea6c-5d56-4a18-b259-4e698ec56f8a
- Source identifiers:
-
237701
- Local pid:
- pubs:237701
- Copyright date:
- 2000
Journal article
Distribution of a persistent sodium current across the ventricular wall in guinea pigs.
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