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Journal article

Distribution of a persistent sodium current across the ventricular wall in guinea pigs.

Abstract:

A tetrodotoxin-sensitive persistent sodium current, I(pNa), was found in guinea pig ventricular myocytes by whole-cell patch clamping. This current was characterized in cells derived from the basal left ventricular subendocardium, midmyocardium, and subepicardium. Midmyocardial cells show a statistically significant (P<0.05) smaller I(pNa) than subendocardial and subepicardial myocytes. There was no significant difference in I(pNa) current density between subepicardial and subendocardial c...

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Publication status:
Published

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Publisher copy:
10.1161/01.res.87.10.910

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
Journal:
Circulation research
Volume:
87
Issue:
10
Pages:
910-914
Publication date:
2000-11-05
DOI:
EISSN:
1524-4571
ISSN:
0009-7330
URN:
uuid:943eea6c-5d56-4a18-b259-4e698ec56f8a
Source identifiers:
237701
Local pid:
pubs:237701

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