Diagnostic use of autoantibodies in myasthenia gravis.

Journal article

The diagnostic use of antibodies is dependent on sensitivity and specificity of the methods of antibody detection, which have been developed and improved over the years. Here, we review the different methods for the detection of acetylcholine receptor and muscle-specific kinase antibodies, which are, so far, the only antibodies recognised as pathogenic in myasthenia gravis (MG). Seronegative MG patients will benefit from more sensitive methods of antibody detection. The most recent developmen...

Expand abstract

Authors: Leite, M; Waters, P; Vincent, A

• Publication status: Published
• Journal: Autoimmunity
• Volume: 43
• Issue: 5-6
• Pages: 371-379
• Publication date: 2010-08-01
• DOI: 10.3109/08916930903541208
• EISSN: 1607-842X
• ISSN: 0891-6934
• Language: English
• Keywords: Autoantibodies; Myasthenia Gravis; Receptors, Cholinergic; Child; Humans; Receptor Protein-Tyrosine Kinases; Enzyme-Linked Immunosorbent Assay; Male; Female; Immunologic Tests; Adult; Fluorescence; Radioimmunoprecipitation Assay